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As reported by the Miami Herald, patients across the region say GLP1 medicines such as Ozempic, Wegovy, Mounjaro and Zepbound have helped with weight, pain and breathing, while fresh studies and regulatory moves are flagging risks that are harder to ignore

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Compared with normal mice, the expression levels of CYP7A1 and CYP27A1 increased in mice whose the TGR 5 gene was knocked out, indicating that TGR5 is involved in inhibiting the expression of CYP7A1 and CYP27A1 (82)

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