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Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation

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It had long been known that the disease was associated with defects in the gastrointestinal tract: patients had chronic gastritis and lack of acid secretion (achlorhydria)

Furthermore, although EMS is a benign disorder, it displays some pathogenic characteristics of malignant diseases (40), such as the tendency to invade and relapse, and adaptation to hypoxia (41)