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Retrieved April 18, 2025

The Dopamine Link: What's Happening in the Brain Experts believe the emotional shift is tied to the brain's dopamine, or reward, system, since GLP-1 receptors are expressed in exactly the circuits linked to reward and pleasure

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Regardless the type of compound, obesogenic effects are mainly mediated through activation of nuclear receptors (especially PPAR- and RXR), disruption of lipid and glucose metabolism, adipocyte differentiation, inflammation, and altered appetite or satiety regulation

This conservative approach means patients often spend weeks simply waiting for natural healing to occur