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The new data suggest that treating the metabolic root cause of the problem with GLP-1 drugs, rather than supplementing the hormone that obesity is suppressing, may be both more effective for those men and far safer for their fertility

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Beyond weight-related improvements, it enhances insulin sensitivity (HOMA-IR reduction of 1.58), lowers fasting blood glucose by 0.30 mmol/L , and boosts SHBG levels by 10.04 nmol/L , which helps address hyperandrogenemia and its associated symptoms

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