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When the first GLP-1 RA, exenatide, was released in 2005, the sole indication was for glycemic control, and weight loss was deemed a favorable side effect

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485,486,489,490 This has compromised any ability to generate definitive evidence supporting the role of regular supplemental L-carnitine in the treatment of these symptoms

As shown in Table 1, with regard to the association of MTHFR gene and its enzyme products, some of the studies revealed severe enzymatic deficiency

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