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Possible side effects of IGF-1 LR3 administration can include [1, 14, 15]: Hyperandrogenism Muscle and joint pain Nausea Headache Impaired glucose metabolism and hypoglycemia Fatigue Changes in sexual function Soft tissue swelling Researchers should thoroughly check glucose, cholesterol, and bone density levels before administering IGF-1 LR3 to test subjects

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doi: 10.1084/jem.181.6.2017

Because the half-life is 20-30 hours, one injection per day produces relatively stable receptor coverage