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A novel enzyme (the bifunctional glutathione synthetase encoded by gshF ) that possessed both -GCS and GS activities and was non-sensitive to GSH was discovered in several microorganisms, including Streptococcus agalactiae [10], Enterococcus faecalis [10], Listeria monocytogenes [11], and Streptococcus thermophiles [12]
Glutathione regulates metabolism of vitamins D, E, and C, earning its designation as the master antioxidant. Age-related GSH decline occurs commonly in advanced age, with defective renal glutathione metabolism marking renal aging
[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Hall KD, Kahan S
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