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A 2009 study gave breast cancer patients 75mg daily for 28 days and found that there were no effects on radiation-induced fatigue or depression.79 And an older study that gave 45 elderly volunteers 1g of guarana found no significant sleep quality, cognitive, or sexual improvements.80 Natural caffeine (from Green Tea) 50mg While there isnt much research on caffeine for female sexual health, the results of a 2023 study showed that, compared to a placebo, acute administration of 300mg of caffeine (around six times the amount in this supplement) increased genital arousal in women experiencing sexual dysfunction due to antidepressants.81 Saffron extract 30mg There are a few positive studies that suggest saffron supplementation may be beneficial for sexual dysfunction

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Mol Divers 30 , 221239 (2026)

Functional targeting of cancer-associated fibroblasts (CAFs) using a combination of DFO and follistatin-like protein 1 (FSTL1) -neutralizing antibody significantly alleviated CAF-induced natural killer cell (NK cell) ferroptosis and boosted the cytotoxicity of NK cells against GC [104]