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Following a switch from metformin HCl immediate-release to saxagliptin and metformin hydrochloride extended-release tablets, closely monitor glycemic control and adjust the dosage accordingly

The final reaction comprises of 2 ml of Na-phosphate buffer (pH 7.3, 0.5 M,) 0.1 ml of enzyme extract, 0.1 ml of EDTA (3 mM) and 0.1 ml of H 2 O 2 (3 mM) for 5 min

Dissolving the Compound Once the solvent has been added, the vial should be swirled gently or rolled between the palms never shaken

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