NICE guidelines (NG87) recommend methylphenidate, lisdexamfetamine, atomoxetine, and guanfacine as first-line pharmacological treatments for ADHD, alongside non-pharmacological approaches such as psychoeducation, CBT, and environmental modifications
Tirzepatide is a new type of glucose-dependent insulinotropic polypeptide (GIP, also known as gastric inhibitory polypeptide) receptor and glucagon-like peptide-1 (GLP-1) receptor dual activation developed by Eli Lilly
Injection site reactions affect roughly 3.2% of tirzepatide users in clinical trials, compared to just 0.4% on placebo
Having glucagon is also super important, and I have definitely used some mini-doses in these experiences
Here, we report the results of experiments with tirzepatide in primary islets, an experimental approach uniquely suited to assess whether tirzepatide directly activates the GIPR in humans