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If fatigue is ongoing, unexplained, or affecting your quality of life, it may be worth exploring whether B12 deficiency is a contributing factor

Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction

Pro Tip: I always recommend using a standard 1 mL (100-unit) insulin syringe for this

The logic here is that the human body releases growth hormone in natural pulses with gaps in between, and this schedule more closely mimics that rhythm

Some individuals on the extreme side of things may even feel as if they are going to die