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Furthermore, GLP-1RA treatment in patients with T2DM has been linked to decreased secretion of pro-inflammatory cytokines, such as interleukin-1 (IL-1), interleukin-6 (IL-6) and tumor necrosis factor- (TNF-) by peripheral blood mononuclear cells (PBMC) [75]

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Several retrospective studies and meta-analyses on the association of DPP-4 inhibitor therapy and pancreatitis have altogether shown a low risk for acute pancreatitis (46, 47)

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