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ARE is involved in the regulation of the expression of various antioxidant enzymes such as SOD, glutathione peroxidase, thioredoxin reductase, and other enzymes (Lismont et al

In laboratory settings, it has been examined for its interaction with GLP-1 pathways and its role in neuroendocrine and metabolic signaling

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Insulin signaling pathway and related molecules: Role in neurodegeneration and alzheimers disease