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Anecdotal/observational reports (body composition, energy, recovery) exist in performance settings, but lack standardized dosing, controls, and validated endpoints

KLOW is excluded during active cancer treatment

Oral spironolactone is a is potassium-sparing diuretic used off-label in the treatment of hormonal acne and female pattern baldness

Mitophagy in PDAC PDAC cells display prominent mitochondrial alterations, including elevated mtDNA mutation rates, enhanced mitochondrial fragmentation, and increased fission activity compared to normal pancreatic tissues [14, 15]

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