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Those trials examined its effect on body weight and fat mass in adults with obesity

10.1074/jbc.M113.493023 24 BernatchezP.SharmaA.BauerP

Markowicz-Piasecka M, Markiewicz A, Darak P, Sikora J, Adla SK, Bagina S, Huttunen KM (2022) Current chemical, biological, and physiological views in the development of successful brain-targeted pharmaceutics

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Most patients notice meaningful change after two months, which corresponds to approximately two full treatment cycles