[3] [2] We examine this route comparison in dedicated detail in our analysis of injectable versus topical GHK-Cu in the skin research literature, and the specific question of systemic exposure in what the research says about subcutaneous and systemic injectable GHK-Cu
It is not mandatory to apply the recommendations, and the guideline does not override the responsibility to make decisions appropriate to the circumstances of the individual, in consultation with them and their families and carers or guardian
**Patch Test:** Before applying to your entire face, perform a patch test on a small, inconspicuous area of your skin (e.g., behind the ear or on the inner forearm), and wait 24 hours to check for any adverse reactions
The disadvantage is that higher doses require large injection volumes
Ottesen AH, Louch WE, Carlson CR, Landsverk OJB, Kurola J, Johansen RF, Moe MK, Aronsen JM, Hoiseth AD, Jarstadmarken H, et al