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Secondary Effects of GLP-1 Agonists: Acute GI Symptoms vs Chronic Gut Microbiome Dysbiosis Some secondary effects of GLP-1 RAs are symptomatic and relatively acute, such as gastrointestinal (GI) changes (constipation, diarrhea, nausea and vomiting), therefore mitigation strategies are well known
Covariates with 90% confidence intervals which were within the 80125% equivalence interval were not considered important
Combined, these mechanisms are studied for effects on appetite, blood-glucose regulation, fat metabolism, and metabolic organs such as the heart and liver
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