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Particularly, the effect of WS on GABA and serotonergic pathways may reduce the activation of the HPA axis, diminishing the secretion of corticotropin-releasing hormone and adrenocorticotropic hormone from the hypothalamus and pituitary, respectively, resulting in lower levels of cortisol released from the adrenal cortex [159]

In individuals with T2DM and CAD, liraglutide also showed LDL-lowering effects, though with very low evidence certainty (Class IV

Adolescents taking these drugs had a lower incidence of suicidal thoughts compared to those who were not

The downside to GLP-1 drugs is that all but one has to be taken by a shot