Well-designed clinical trials in humans are needed
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On the other hand, the purposeful cytoprotective conceptualization of muscle disturbances with cytoprotective agents might be worthy, given Roberts and Szabos original prostaglandin cytoprotection (stomach) background [35,36,37,38,39,40,41,42], cytoprotection as a commonly acknowledged ongoing physiologic process [83] and prostaglandin E2 as a crucial inflammatory mediator of muscle stem cells and as the building blocks of muscle regeneration [84]
