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Read the analysis: Michael Weintraub, MD Neil Iyengar Stephen Nicholls To view or add a comment, sign in Tirzepatide in SURPASSCVOT: Noninferior CV outcomes vs dulaglutide, with superior weight, A1c, BP, lipids, and renal benefits in T2D with ASCVD

For example, in the STEP 1 trial , patients taking semaglutide lost an average of 14.9% of their body weight over 68 weeks , compared with just 2.4% in the placebo group (NEJM study)

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These changes typically reflect the body's hormonal response to a meaningful reduction in caloric intake or fat mass