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Oxidative damage in nucleic acids and Parkinsons disease

Chemopreventive functions and molecular mechanisms of garlic organosulfur compounds

g i ) Representative whole dorsal striatal images of NPY immunofluorescence from Trkb Penk-WT control ( g ), Trkb Penk-KO mutant injected at 3 M with Gsto2 -shRNA ( h ) or scrambled-shRNA in the striatum ( i ) and analysed at 15 W

Did you know these free radicals can even impact DNA and cells? Even some of the most notorious free radicals such as advanced glycation end products (AGEs), and reactive oxygen species (ROS) can be squelched by the free radical fighting antioxidant support of glutathione.

While free radicals are a natural part of the bodys functioning, an overabundance can lead to oxidative stress, resulting in cellular damage and contributing to various chronic diseases (Zakeri et al., 2021)