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For example, some diabetic patients who experience gastrointestinal side effects from standard doses of GLP-1 receptor agonists may benefit from a slower dose escalation to reduce discomfort

Lancet 2: 1300-1304, 1987

Dissolve the bloomed gelatin: Transfer the hot juice mixture into the bowl containing the bloomed gelatin

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Key features Sensitive and easy-to-use colorimetric SEAP bioassay Convenient readout using QUANTI-Blue Solution Strong response to GLP-1R agonists Suitable for kinetic studies (no cell lysis required) Stability guaranteed for 20 passages Applications Therapeutic development Drug screening Release assay Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced primarily by intestinal L-cells in response to rising glucose concentrations