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Conservative approaches start at 0.2-0.25 mg, while acute injuries may warrant 0.5-0.75 mg daily split into two doses

370 Additionally, mTOR1 also phosphorylates and inhibits eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1), which downregulates the expression of Cyclin D1

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Boruah JS, Devi C, Hazarika U, Bhaskar Reddy PV, Chowdhury D, Barthakur M, et al