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Description

260 GLP-1 downregulated Na+/H+ exchanger isoform 3 in the renal proximal tubule of rats, suggesting that GLP-1 could be used to treat hypertension and sodium retention disorders

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In animal studies, some GLP-1s have shown harmful effects on developing foetuses, which has led to caution around use in pregnancy and breastfeeding

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Thomson, S

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Zepbound vs Wegovy: what patients usually want to know When patients ask their providers to compare Zepbound and Wegovy, the conversation usually comes down to three main factors: Mechanism of Action: Wegovy (semaglutide) works through the GLP-1 receptor alone

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