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The largest study to date that analyzed patterns of GLP1 RA use in breast cancer survival was a retrospective study that analyzed roughly 1022 patients with nonmetastatic (DCIS or invasive stage IIII) at MD Anderson Cancer Center who received at least 3 months of semaglutide and tirzepatide

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Berberine is a natural alkaloid extracted from plants, while GLP-1 agonists like semaglutide are synthetic peptides that mimic the glucagon-like peptide-1 hormone

It's what they are doing alongside it

This places it in the same category as many research peptides, available through certain channels but without official sanction for human use