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Essa constatao levou hiptese de que a reduo natural do GHK poderia estar associada s alteraes observadas na capacidade de renovao dos tecidos durante o processo de envelhecimento, estimulando uma nova linha de pesquisas voltada ao papel desse peptdeo na biologia cutnea

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Other small molecule inhibitors have also been reported, including those derived from amino adenosine and other nicotinamide-related compounds 206,207,208

A 1992 study by Hartman et al