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In Phase 2 obesity trials, retatrutide produced approximately 24% mean body-weight reduction at 48 weeks at the 12 mg dose the largest weight-loss effect reported for any GLP-1-class compound to date

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Understanding metabolic memory: the prolonged influence of glycemia during the Diabetes Control and Complications Trial (DCCT) on future risks of complications during the study of the epidemiology of diabetes interventions and complications (EDIC)

"Anybody who's 500 pounds: I don't care if you take one shot or 10," he emphasized