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Six participants cannot define a treatment effect A crossover design can be useful for exploratory research, but a study involving six people cannot establish uncommon risks, long-term effectiveness or suitability for people with different health conditions

Thus, while GH is a positive regulator of extracellular matrix (ECM) synthesis (Kragstrup et al., 2011) which is important in morphogenesis (Rozario and DeSimone, 2010), there is still debate surrounding its role in the regulation of muscle mass in adults

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Oxidative stress and Nrf2 in the pathophysiology of diabetic neuropathy: old perspective with a new angle

doi: 10.1016/j.jaut.2023.103050