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10.1111/apha.13611 Acta Physiol (Oxf)

There are several categories of enzymes involved in the metabolism of lipophilic xenobiotics and their conversions into less toxic compounds exhibiting increased hydrophilicity (Figure 2)

From our initial review of 2026 formularies, heres what were seeing: Coverage: All 2026 MFP drugs are currently covered but they can be swapped for generics or biosimilars later (e.g., Stelara, Entresto, Farxiga) Tiering changes: Largely unchanged from 2025