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Food and Drug Administration approved Foundayo (orforglipron) for adults with obesity, or for adults who are overweight and have at least one weight-related medical condition such as high blood pressure, type 2 diabetes, or high cholesterol

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doi: 10.3390/nu5062062, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 40

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l-valine is a powerful stimulator of GLP-1 secretion in rodents and stimulates secretion through ATP-sensitive potassium channels and voltage-gated calcium channels