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London: University College London

The Legacy Physicians Approach At Legacy Physicians, we welcome this new treatment option as another tool for personalized patient care

For example, in 2023, the European Medicines Agency began investigating over 150 reports of suicidal ideation and other psychiatric symptoms linked to GLP-1 receptor agonists, including Ozempic and Wegovy

The STEP clinical trials demonstrated mean weight losses of 14.9% to 17.4% in participants with overweight or obesity, with 69% to 79% achieving at least 10% weight loss

When experiments include receptor-selective controls, they can disentangle which pathway drives each measured effect, improving interpretability