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Seek urgent medical attention (call NHS 111 or go to A&E) if you experience severe, persistent abdominal pain (especially if radiating to the back or right upper quadrant), fever with abdominal pain, persistent vomiting, or yellowing of the skin or eyes (jaundice)

Inhibition of PHGDH effectively reduces glycine availability and has been shown to alleviate fibrosis in experimental models [18]

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31 Combination of Ag + with negatively charged membrane perforates the membrane, thus allowing cytoplasmic contents to flow out of the cell, dissipating the H + gradient across the membrane and sometimes causing cell death

Dehydration associated with gastrointestinal side effects like nausea and vomiting can concentrate blood volume, potentially affecting blood pressure regulation in susceptible patients