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Eligibility criteria Studies were included if they met the following criteria, according to the PICOS framework: Population Adults ( 18 years) only at high risk for cardiovascular disease (CVD) or with established CVD (coronary artery disease, heart failure, prior myocardial infarction, stroke)

Private insurers might have more flexibility, but only if the notes are clear and the medical necessity is solid

Because a significant portion of oral carnitine remains unabsorbed in the gastrointestinal tract, it interacts heavily with the gut microbiome

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