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Firstly, reliance on diagnostic codes for disease classification might have resulted in an underrepresentation of mild cases, potentially leading to ascertainment bias

This test measures levels of key neurotransmitters, such as serotonin, dopamine, and norepinephrine, which play critical roles in regulating mood, cognition, and overall mental health

doi:10.1093/emboj/18.11.3133

Differentiating Changes in Glutathione Levels from Cytotoxic Events Using Multiplexed Assays Alisha Truman and Brad Hook Promega Corporation Publication Date: October 2013 Abstract Measuring changes in glutathione levels as a single endpoint may not be sufficiently informative to differentiate a decrease in GSH from a cytotoxic event