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Collagen and elastin preservation Oxidative stress accelerates the breakdown of collagen and elastin through activation of matrix metalloproteinases (MMPs)

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In a 2017 study using human vascular endothelial cells and a chick chorioallantoic membrane assay, Hsieh and colleagues reported that BPC-157 exposure increased VEGFR2 mRNA and protein expression, promoted VEGFR2 internalization (an effect blocked by the endocytosis inhibitor dynasore), and time-dependently activated the VEGFR2-Akt-eNOS axis without a corresponding increase in VEGF-A (Hsieh et al., 2017)

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They could also ease oxidative stress by mopping up chemically reactive oxygen molecules with an FDA-approved antioxidant called N-acetylcysteine, or NAC, thats already used to help treat children with cystic fibrosis