gip/glp-1 receptor agonist GIP Agonism Attenuates GLP-1 Receptor Induced Nausea and Emesis in Preclinical Models — Hayes Lab Demonstrated metabolic effects of GIP,

Strikingly, simply increasing mitochondrial GSH levels by expressing mito-GSHf in SLC25A39/40 double knockout cells completely restored the reduced levels of mitochondrial translation machinery proteins, iron-sulfur containing proteins, and aconitase activity (Fig 4f,g)

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Ablation of the ferroptosis inhibitor glutathione peroxidase 4 in neurons results in rapid motor neuron degeneration and paralysis

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