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Pregnancy and lactation safety has not been systematically studied, and as with most cosmetic and research compounds lacking definitive pregnancy safety data, conservative practice typically suggests avoiding use during pregnancy unless clearly needed, though the natural occurrence of GHK-Cu in the body and minimal systemic absorption from topical use suggest risk is likely to be low

Wound and Tissue-Response Models (preclinical): Used in experimental settings that measure connective tissue and repair-related endpoints

Abbas et al., 2023b

Front Bioeng Biotechnol (2015) 3:23

The body will only absorb a small amount when ingested orally