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Oxidative stress is commonly discussed in the context of illness and physiologic strain in dogs, and antioxidant supplementation has been proposed as supportive care in those situations (Hagen DM, 2019)

A similar pattern is observed in gastrointestinal infections, where pathogens such as Salmonella enterica invade Peyers patches in the intestinal epithelium, penetrate immune cells like macrophages and dendritic cells, and disseminate to mesenteric lymph nodes, spleen, and bone marrow

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