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The GLP1RA exenatide ameliorates drug-induced ROS production in neurons by increasing expression of the base excision repair protein, APE1, and activating this geno-protective pathway in vitro and in vivo [102]

While their glycemic, weight-lowering, and cardiovascular benefits are well established through randomized trials and meta-analyses, concerns remain regarding their safety and tolerability across diverse populations and clinical settings

Studies have shown that silencing HKII in CRC cell lines such as HT-29, SW480, HCT-15, RKO, and HCT-116 can effectively halt their proliferation and high EMP activity [48]

(Dry mouth, enamel erosion, nausea/vomiting, dietary changes, caries risk) MDPI Biology Journal

doi: 10.1016/S0162-0134(02)00511-1