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Part of the reason is that, while some studies showed strong effects in controlled settings, the evidence was limited (small sample sizes, shortterm)

The more serious concern with phentermine is the cardiovascular risk associated with prolonged use

The MHRA has licensed several GLP-1 agonists for use in the UK, and NICE guidelines (NG28) recommend them for specific patient groups, particularly those with type 2 diabetes who have not achieved adequate control with other medications or who have additional cardiovascular risk factors

In the assessment of tophi, DECT enables accurate quantification of tophi, clearly displaying their size, distribution, and relationship with surrounding tissues, outperforming traditional imaging modalities

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