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When the list price of a drug is announced, insurance companies and Pharmacy Benefit Managers (PBMs) step in to negotiate with the drug manufacturers

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10.1021/acs.jmedchem.5b00726 36 LeanM

Conflict of interest The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

Potential side effects, even at lower doses, include nausea, mild digestive discomfort, and fatigue