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These rapid mood fluctuations, particularly the emergence or intensification of depressive and anxious states, can significantly disrupt daily functioning and interactions with others, severely impacting an individual's overall well-being

Kaminishi H, Hagihara Y, Hayashi S, Cho T

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

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All hypertensive patients had no clinical signs, symptoms and laboratory findings suggesting secondary hypertension