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The GLP-1RA group reported lower subjective feelings of intoxication during the early timepoints of the session, as indicated by reduced ratings on the Visual Analog Scale (VAS) for How drunk do you feel?

Worth noting: Sugary cocktails and mixers add to the blood sugar spike and crash, which worsens the 3am wake-up

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Because the peptide occurs naturally in human plasma (at roughly 200 ng/mL in young adults, declining to approximately 80 ng/mL by age 60), topical supplementation essentially restores youthful local concentrations in treated skin