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4 Effect of MK-677 on mRNA and protein expression of growth hormone (GH), GH-releasing hormone (GHRH), GH secretagogue receptor (GHSR), somatostatin (SST), somatostatin receptor (SSTR)-2, and SSTR-5 in the hypothalamus or pituitary gland

Bregovskii, V

Eur Rev Med Pharmacol Sci (2019) 23(5):1899906

Western blots, activity gels and activity assays are various methods used to determine protein and activity in both cells and tissue depending on the amount of protein required for each assay

The theoretical rationale for combining these peptides is soundthey work through complementary mechanismsbut actual safety and efficacy data for this specific combination does not yet exist in published literature