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Understanding these human-specific interactions will be vital for optimizing therapeutic strategies

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Unlike fulllength hGH, AOD9604 does not meaningfully elevate IGF1 levels or worsen glucose tolerance, making its tolerability indistinguishable from placebo in human trials [2] [3]

Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins