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In this way, therapeutically clearing senescent cells, even neurons, may prove beneficial as supported by experimental data in transgenic mice (3537)

Muscle crush injury Right hind limbs were shaved, and using special system a force of 0.727 Ns/cm2 was delivered to a maximum diameter of gastrocnemius muscle complex 2 cm proximal to the insertion of the Achilles tendon (12)

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The primary consideration is injection site management: rotating sites to avoid localized irritation and ensuring each injection reaches subcutaneous tissue without overlap