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The peptide is typically supplied in lyophilized (freeze-dried) powder form and requires reconstitution with bacteriostatic water before injection

Shelf Life: Once reconstituted, the solution should be refrigerated at 2C to 8C and utilized within 14 to 21 days to ensure maximum potency

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Data from the ORION study, presented at the Obesity Medicine Associations 2026 annual conference, showed that oral semaglutide 25 mg was associated with significantly greater mean weight loss than orforglipron in a population-adjusted indirect treatment comparison