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One hundred and fifty-nine patients with mild GO were randomized to receive sodium selenite (100 mcg twice/day, equivalent to 91.3 g of selenium), pentoxifylline (600 mg twice/day), or placebo (twice/day) for 6 months, followed by a follow-up period of 6 months

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[DOI] [PubMed] [Google Scholar] 77.Bello NT, Zahner MR

Li et al demonstrated that vitamin B12 may up-regulated insulin like growth factor-1 (IGF-1) gene expression, and showed a better neuroprotective effect in the presence of good control of hyperglycemia in rats with diabetic peripheral neuropathy 20