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DAMPs display notable heterogeneity in their expression across various diseases and even at different stages of the same disease, considerably escalating the difficulty of achieving precise regulation

Limited clinical data

Different clinical symptoms reported in individual patients with 5-oxoprolinase deficiency are renal stone formation, enterocolitis, mental retardation, neonatal hypoglycemia, microcytic anemia and microcephaly [4045]

doi: 10.1016/j.regpep.2013.03.026

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