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How do GIP/GLP1 dual medications work

PubMed Central , Archives of Medical Science : AMS , vol

Clinical Trial Results: Weight Loss & Key Outcomes Phase 2 (Published in NEJM & Nature Medicine) Obesity trial (NEJM 2023): Up to 24.2% mean weight loss at 48 weeks (12 mg dose)

Like other copper-binding tripeptides, its biological effects are proposed to occur through both the peptide backbone and the copper ion it coordinates with the copper contributing to enzymatic cofactor activity and oxidative stress modulation